Slide Scanning at Your Microscope

Microlucida gives you the power to capture 2D and 3D whole slide images at your brightfield or fluorescence microscope. It also enables you to use a single high-quality image acquisition application across all of your microscopes, a feature particularly beneficial for core facilities.

  • With support for research microscopes from Zeiss, Olympus, Nikon, and Leica, Microlucida is custom-designed for seamless integration with the world's leading motorized stages and cameras.
  • Microlucida can save large amounts of disk space with its high-quality JPEG 2000 compression of images and stacks. 
  • Capture stunning whole slide images for your research with Microlucida.

We work closely with you to choose the best hardware for each new system, ensuring optimal performance to help you achieve your research goals within your budget.  Our software can integrate with most existing microscopes if you already own microscope equipment, or we can provide you with all necessary hardware components.

Microlucida is designed to operate on a wide variety of microscopes and hardware commonly used in laboratories.  This versatility allows customization of your research system to fit your exact needs and budget.

We encourage you to contact us with any questions, as the functionality of the system and the hardware needed is dependent on your research goals.

System Components

  • Microlucida software 
  • Research microscope
  • Motorized microscope stage and focus
  • Scientific grade digital camera
  • Specialized microscope hardware (filter wheels, shutters, vibration isolation platforms, z-encoders, structured illumination, digitizing tablets)
  • PC running Microsoft Windows 7 or 8

Supported Hardware

Microlucida software integrates with many types of research microscopes. Here is a list of some of the microscope hardware that we support:

Microscopes (both manual and fully motorized): Zeiss, Nikon, Leica, Olympus

Digital cameras: Hamamatsu, Q Imaging, Optronics, Cooke, Photometrics, MBF, Olympus, Leica, Zeiss, DVC, hundreds of Firewire camera models

Video cameras: Most legacy NTSC or PAL video cameras

Motorized XY stages: Ludl, Märzhäuser, Objective Imaging, Prior, ASI, Zeiss

Focus encoders: Heidenhain, Boeckeler

Laser scanning confocal microscopes: Full integration: Zeiss LSMs

Semi integration: Nikon, Leica, Olympus FluoView, SAR Procyon laser illuminator

Structured illumination hardware: ApoTome, ApoTome II, Qioptiq Optigrid, Olympus DSU, BD Biosciences CARV-II

Vibration isolation platforms: Vistek, Newport

External motorized filter wheels/shutters: Ludl, Prior, Uniblitz, Sutte

Digitizing data & video tablets: Wacom

We can provide you with a complete turn-key system solution, ensuring maximum performance, reliability, and ease-of-use. We stand fully behind every system we sell.

Stereo Investigator and Neurolucida systems run on the same hardware platform and are available in two separate configurations:

  • Standard – controls microscope hardware (and includes support for working with images or Biolucida)
  • Workstation – does not include hardware control (for working with image files or Biolucida)

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Professional Technical Support

When you call us you will speak with a person - not an automated system. Talk to us about your hardware, software, or experimental design questions. Our team includes Ph.D. neuroscientists and experts in microscopy, stereology, neuron tracing, and image processing; ready to help you over the phone or online.

Visit our Technical Support Center

Digital Cameras

We support the world leading manufacturers of scientific grade digital cameras. We help you chose the model that is most effective for your use–from real-time color cameras for brightfield microscopy to state-of-the-art cooled, high sensitivity cameras for dim fluorescence microscopy. We can also configure systems with dual cameras to optimally support the widest range of specimens – from brightfield microscopy through structured illumination fluorescence microscopy.

Motorized Stages

Microlucida is most productive and efficient with a three-axis motor driven microscope stage. The software automatically maintains the registration of the graphics overlay with the microscope image when the stage is moved, allowing for integration of multiple fields of view. This feature ensures the fastest and most accurate data acquisition from objects larger than a single field of view.

Specialized Microscope Hardware: motorized external filter wheels, shutters and illumination devices

When working with multi-channel fluorescence microscopy we automate many of the functions of a microscope to dramatically reduce the amount of work that you need to do, such as changing fluorescence filters and opening and closing the shutter. We can add automatic, motorized devices to most existing manual microscopes.


We are an authorized reseller of Dell computers, monitors and peripherals. We can easily work with you to ensure a complete, customized, economical integrated solution.

The recommended computer configuration includes: PC with Intel Core i7 (or AMD processor with similar benchmarks), Microsoft Windows 7 (32 or 64 bit*) Windows 8  (32 or64 bit*), 12 GB or more RAM (minimum 2GB), 100 GB or larger hard drive (minimum 40GB), and dual monitors (24” 1920×1200).

*For 64-bit, we include a true 64-bit application with signed 64-bit drivers, allowing the loading of much larger 3D image stacks, images and videos.

Although we support a wide range of hardware, certain hardware configurations are not appropriate for some applications. We recommend you contact us for details.

Still Have Questions? Just Ask!